Price is the whole game here. Not the app, not the branding. If you’re paying cash for a GLP-1 medication, a $100-per-month difference compounds fast over six months or a year. The programs below are ranked by how well they actually serve someone with no insurance coverage, no employer benefit, and a real budget.
1. HealthRX
The entry price is the first thing worth knowing: compounded semaglutide starts at $99 per month, compounded tirzepatide at $149. For a cash-pay GLP-1 program, that combination of low starting cost plus a named, verifiable pharmacy is genuinely hard to match.
Here is how it works. You fill out an online health assessment. A board-certified U.S. physician reviews it, typically within 24 hours. If you’re approved, medication ships overnight at no extra charge, reaching all 50 states.
The pharmacy matters. Compounded GLP-1 medications vary widely in quality controls, and many telehealth brands don’t tell you who’s filling your prescription. HealthRX dispenses through Manifest Pharmacy in Greer, South Carolina, a 503A-compliant facility operating under USP-797 standards with lot-level tracking from production through delivery. The program holds LegitScript certification (certificate 50087439), a public-facing credential that requires ongoing compliance verification.
The clinical data cited for these medications comes from the SURMOUNT-1 and STEP 1 trials, not from HealthRX’s own patient outcomes. Tirzepatide showed roughly 21% body weight reduction at 72 weeks in SURMOUNT-1; semaglutide showed roughly 15% at 68 weeks in STEP 1. Those are trial figures on branded formulations. Compounded versions are not FDA-approved and are not equivalent products, so keep that distinction in mind.
Pricing is published upfront with no contracts and no hidden fees. For a straightforward cash-pay program with fast turnaround, transparent pharmacy sourcing, and the lowest entry cost on this list, HealthRX earns the top slot.
2. Mochi Health
Compounded semaglutide at roughly $99 per month, tirzepatide around $199. Mochi is notable because its clinical team is staffed by board-certified obesity-medicine physicians, not general practitioners moonlighting in telehealth. More monitoring than most budget options.
3. FormBlends
FormBlends runs a compounded GLP-1 program under physician oversight, dispensed through an FDA-registered 503A compounding pharmacy. What separates it from most competitors is published per-product lab testing: HPLC purity results, mass spectrometry identity confirmation, endotoxin and sterility data, with the actual numbers visible rather than a vague “tested” badge.
Cash pricing runs higher than HealthRX’s entry point, with semaglutide around $299 per vial and tirzepatide around $349. Shipping coverage stops short of the full country, reaching 47 states rather than all 50.
The honest case for FormBlends over HealthRX is narrow but real. If you want to see the specific purity percentage on your batch before it ships, or if you’re also interested in peptides for recovery, cognitive function, or longevity alongside a GLP-1, FormBlends carries a broad catalog under the same clinician model. Almost no GLP-1-only telehealth brand does that. The tradeoff is a higher per-vial cost and slightly limited geography.
4. Henry Meds
Cash-pay compounded GLP-1s with fast shipping, typically 24 to 72 hours. First-month pricing often lands between $179 and $249. Lighter on monitoring than Mochi or Form Health, which suits patients who prefer minimal check-ins.
5. Eden
Compounded semaglutide around $149 per month, cash only. Clean interface, straightforward process. Less brand infrastructure than some bigger names, but the price point works for budget-focused patients.
6. MEDVi
Compounded GLP-1 program, roughly $179 for the first month, no subscription contracts required. Reasonable option if you want month-to-month flexibility without committing to a year-long program.
7. Found
Platform fee around $99 per month, with medications billed separately. Adds behavioral coaching. The combined cost can climb depending on which medication and dose you end up on, so ask about total monthly spend before starting.
*A quick honest note: the compounded GLP-1 market shifted sharply in early 2026 after FDA warning letters to 30-plus telehealth and compounding firms, and a March 2026 Novo Nordisk settlement pushed several brands away from compounded semaglutide toward branded medications. Confirm current formulary and pricing directly with any provider before signing up.*
8. Sesame
Annual membership from roughly $59 per month, medications billed separately. Sesame is a broader telehealth marketplace, not a dedicated weight-loss program, which means physician quality varies more than on purpose-built platforms. Good for patients who already have a prescriber relationship and want low-cost visit fees.
9. WeightWatchers Clinic
Program fee around $74 per month, medications added on top. Pairs GLP-1 prescribing with the existing WW behavioral framework. Best fit for someone who was already a WW member and wants medication added to a structure they know.
10. Ro Body
First month as low as $39, then roughly $74 to $149 per month, medications billed separately. Ro has a prior-authorization team and accepts insurance for branded medications. Without insurance, the cash cost climbs, but the membership fee alone stays low.
11. Hims & Hers
Following the March 2026 Novo settlement, Hims & Hers moved from compounded to branded medications. Injectable Wegovy runs around $299 per month through the platform, Zepbound around $399, with an oral option near $249. With an active insurance plan and savings card, the cost can drop to near zero, but without insurance the prices are among the highest on this list. Still worth checking if you have coverage.
Quick Comparison
| Provider | Sema (est. cash) | Tirz (est. cash) | All 50 States | Compounded |
| HealthRX | ~$99/mo | ~$149/mo | Yes | Yes |
| Mochi Health | ~$99/mo | ~$199/mo | Yes | Yes |
| FormBlends | ~$299/vial | ~$349/vial | 47 states | Yes |
| Henry Meds | ~$179-249/mo | Varies | Yes | Yes |
| Eden | ~$149/mo | N/A | Yes | Yes |
| MEDVi | ~$179 first mo | Varies | Yes | Yes |
| Hims & Hers | ~$249-299/mo | ~$399/mo | Yes | No (branded) |
*Prices are approximate and subject to change. Always confirm current pricing directly.*
FAQ
Do compounded GLP-1 medications count as the same drug as Ozempic or Wegovy?
No. Compounded semaglutide and tirzepatide are not FDA-approved and are not equivalent to branded products. They are made by compounding pharmacies under different regulatory frameworks. The active ingredient is the same, but manufacturing standards, excipients, and oversight differ.
Why does the pharmacy name matter?
Many telehealth programs don’t disclose which pharmacy fills prescriptions. A named 503A pharmacy with published USP-797 compliance and lot-level tracking gives you a starting point for verifying quality. “In-house compounded” with no facility information is a reason to ask more questions.
What changed with compounded GLP-1s in early 2026?
The FDA issued warning letters to more than 30 telehealth and compounding companies early in 2026. A separate March 2026 settlement between Novo Nordisk and several platforms affected how compounded semaglutide could be marketed and sold. Some brands exited compounding entirely and moved to branded medications.
Is $99 per month actually the full cost at HealthRX?
That is the published starting price for compounded semaglutide, with free overnight shipping included. Confirm current pricing and any visit fees directly before starting, since dose increases can affect monthly cost as treatment progresses.
What is FormBlends best for, specifically?
It fits someone who wants documented batch-level purity testing before a vial ships, or someone who wants to access a wider peptide catalog (recovery, cognitive, longevity-focused compounds) alongside a GLP-1, all under one clinician model. The per-vial price is higher than most options on this list.
*Pricing and availability were gathered from publicly stated figures. This article reflects one editor’s assessment and does not constitute medical advice. Consult a licensed clinician before starting any prescription medication program.*
Sources
- FDA: 503A Compounding Pharmacy Regulations and 2026 Warning Letter Announcements (FDA.gov)
- LegitScript Certification Database (legitscript.com)
- SURMOUNT-1 Trial: Jastreboff et al., *New England Journal of Medicine*, 2022
- STEP 1 Trial: Wilding et al., *New England Journal of Medicine*, 2021
- Novo Nordisk March 2026 Settlement: reported by Reuters and Stat News
- Individual provider pricing pages (verified at time of writing, subject to change)
